Loss of Frizzled 9 in Lung Cells Alters Epithelial Phenotype and Promotes Premalignant Lesion Development

The transmembrane receptor Frizzled 9 (FZD9) is important for fetal neurologic and bone development through both canonical and non-canonical WNT/FZD signaling. In the adult lung, however, Fzd9 helps to maintain a normal epithelium by signaling through peroxisome proliferator activated receptor γ (PP...

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Detalles Bibliográficos
Autores principales: Sompel, Kayla, Dwyer-Nield, Lori D., Smith, Alex J., Elango, Alamelu P., Vanderlinden, Lauren A., Kopf, Katrina, Keith, Robert L., Tennis, Meredith A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343062/
https://www.ncbi.nlm.nih.gov/pubmed/35924166
http://dx.doi.org/10.3389/fonc.2022.815737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343062/
https://www.ncbi.nlm.nih.gov/pubmed/35924166
http://dx.doi.org/10.3389/fonc.2022.815737

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