Distribution- and Metabolism-Based Drug Discovery: A Potassium-Competitive Acid Blocker as a Proof of Concept

Conventional methods of drug design require compromise in the form of side effects to achieve sufficient efficacy because targeting drugs to specific organs remains challenging. Thus, new strategies to design organ-specific drugs that induce little toxicity are needed. Based on characteristic tissue...

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Detalles Bibliográficos
Autores principales: Wang, Ming-Shu, Gong, Yi, Zhuo, Lin-Sheng, Shi, Xing-Xing, Tian, Yan-Guang, Huang, Chang-Kang, Huang, Wei, Yang, Guang-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343080/
https://www.ncbi.nlm.nih.gov/pubmed/35958113
http://dx.doi.org/10.34133/2022/9852518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343080/
https://www.ncbi.nlm.nih.gov/pubmed/35958113
http://dx.doi.org/10.34133/2022/9852518

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