Immunoglobulin gene sequence analysis in chronic lymphocytic leukemia: the 2022 update of the recommendations by ERIC, the European Research Initiative on CLL

The somatic hypermutation (SHM) status of the clonotypic immunoglobulin heavy variable (IGHV) gene is a critical biomarker for assessing the prognosis of patients with chronic lymphocytic leukemia (CLL). Importantly, independent studies have documented that IGHV SHM status is also a predictor of res...

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Detalles Bibliográficos
Autores principales: Agathangelidis, Andreas, Chatzidimitriou, Anastasia, Chatzikonstantinou, Thomas, Tresoldi, Cristina, Davis, Zadie, Giudicelli, Véronique, Kossida, Sofia, Belessi, Chrysoula, Rosenquist, Richard, Ghia, Paolo, Langerak, Anton W., Davi, Frédéric, Stamatopoulos, Kostas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343247/
https://www.ncbi.nlm.nih.gov/pubmed/35614318
http://dx.doi.org/10.1038/s41375-022-01604-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343247/
https://www.ncbi.nlm.nih.gov/pubmed/35614318
http://dx.doi.org/10.1038/s41375-022-01604-2

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