Cargando…

Immunoglobulin gene sequence analysis in chronic lymphocytic leukemia: the 2022 update of the recommendations by ERIC, the European Research Initiative on CLL

The somatic hypermutation (SHM) status of the clonotypic immunoglobulin heavy variable (IGHV) gene is a critical biomarker for assessing the prognosis of patients with chronic lymphocytic leukemia (CLL). Importantly, independent studies have documented that IGHV SHM status is also a predictor of res...

Descripción completa

Detalles Bibliográficos
Autores principales:	Agathangelidis, Andreas, Chatzidimitriou, Anastasia, Chatzikonstantinou, Thomas, Tresoldi, Cristina, Davis, Zadie, Giudicelli, Véronique, Kossida, Sofia, Belessi, Chrysoula, Rosenquist, Richard, Ghia, Paolo, Langerak, Anton W., Davi, Frédéric, Stamatopoulos, Kostas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343247/ https://www.ncbi.nlm.nih.gov/pubmed/35614318 http://dx.doi.org/10.1038/s41375-022-01604-2

Ejemplares similares

Immunoglobulin gene sequence analysis in chronic lymphocytic leukemia: updated ERIC recommendations
por: Rosenquist, R, et al.
Publicado: (2017)

Challenges and Solutions for Collecting and Analyzing Real World Data: The Eric CLL Database as an Illustrative Example
por: Chatzidimitriou, Anastasia, et al.
Publicado: (2020)

Assessing Patients’ Knowledge on Chronic Lymphocytic Leukemia: Validation of the ERIC CLL Knowledge Questionnaire in Greece
por: Karamanidou, Christina, et al.
Publicado: (2021)

P605: IMMUNOGENETICS AND ANTIGEN REACTIVITY PROFILING CONTRIBUTE TO UNRAVELLING THE ONTOGENY OF CLL STEREOTYPED SUBSET #4
por: Iatrou, Anastasia, et al.
Publicado: (2023)

Immunoglobulin gene analysis in chronic lymphocytic leukemia in the era of next generation sequencing
por: Davi, Frédéric, et al.
Publicado: (2020)

Distinctive Signaling Profiles With Distinct Biological and Clinical Implications in Aggressive CLL Subsets With Stereotyped B-Cell Receptor Immunoglobulin
por: Gerousi, Marina, et al.
Publicado: (2021)

Automated shape-based clustering of 3D immunoglobulin protein structures in chronic lymphocytic leukemia
por: Polychronidou, Eleftheria, et al.
Publicado: (2018)

Infrequent “chronic lymphocytic leukemia-specific” immunoglobulin stereotypes in aged individuals with or without low-count monoclonal B-cell lymphocytosis
por: Agathangelidis, Andreas, et al.
Publicado: (2021)

Evidence of somatic hypermutation in the antigen binding sites of patients with CLL harboring IGHV genes with 100% germline identity
por: Sofou, Electra, et al.
Publicado: (2022)

B Cell Receptor Immunogenetics in B Cell Lymphomas: Immunoglobulin Genes as Key to Ontogeny and Clinical Decision Making
por: Gemenetzi, Katerina, et al.
Publicado: (2020)

Immunoglobulin heavy variable somatic hyper mutation status in chronic lymphocytic leukaemia: on the threshold of a new era?
por: Langerak, Anton W., et al.
Publicado: (2020)

Cytogenetics in Chronic Lymphocytic Leukemia: ERIC Perspectives and Recommendations
por: Baliakas, Panagiotis, et al.
Publicado: (2022)

Other malignancies in the history of CLL: an international multicenter study conducted by ERIC, the European Research Initiative on CLL, in HARMONY
por: Chatzikonstantinou, Thomas, et al.
Publicado: (2023)

COVID-19 severity and mortality in patients with CLL: an update of the international ERIC and Campus CLL study
por: Chatzikonstantinou, Thomas, et al.
Publicado: (2021)

Comparative analysis of targeted next-generation sequencing panels for the detection of gene mutations in chronic lymphocytic leukemia: an ERIC multi-center study
por: Sutton, Lesley-Ann, et al.
Publicado: (2020)

TRIP - T cell receptor/immunoglobulin profiler
por: Kotouza, Maria Th., et al.
Publicado: (2020)

IgIDivA: immunoglobulin intraclonal diversification analysis
por: Zaragoza-Infante, Laura, et al.
Publicado: (2022)

Understanding Monoclonal B Cell Lymphocytosis: An Interplay of Genetic and Microenvironmental Factors
por: Galigalidou, Chrysi, et al.
Publicado: (2021)

Prognostic impact of prevalent chronic lymphocytic leukemia stereotyped subsets: analysis within prospective clinical trials of the German CLL Study Group
por: Jaramillo, Sonia, et al.
Publicado: (2019)

P1517: HUMORAL AND CELLULAR IMMUNE RESPONSES TO SARS-COV-2 NATURAL INFECTION OR VACCINATION IN PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA (CLL): A STUDY BY ERIC, THE EUROPEAN RESEARCH INITIATIVE ON CLL
por: Campanella, Alessandro, et al.
Publicado: (2023)

Context-dependent T-cell Receptor Gene Repertoire Profiles in Proliferations of T Large Granular Lymphocytes
por: Assmann, Jorn L.J.C., et al.
Publicado: (2023)

COVID-19 severity and mortality in patients with chronic lymphocytic leukemia: a joint study by ERIC, the European Research Initiative on CLL, and CLL Campus
por: Scarfò, Lydia, et al.
Publicado: (2020)

Immunoglobulin Gene Repertoire in Chronic Lymphocytic Leukemia: Insight into Antigen Selection and Microenvironmental Interactions
por: Kostareli, Efterpi, et al.
Publicado: (2012)

S149: OTHER MALIGNANCIES IN THE HISTORY OF CLL: THE FINAL ANALYSIS OF THE INTERNATIONAL MULTICENTER STUDY CONDUCTED BY ERIC, IN HARMONY.
por: Chatzikonstantinou, Thomas, et al.
Publicado: (2023)

P1222: ANTIGEN-INDEPENDENT, CELL-AUTONOMOUS SIGNALING IN SPLENIC MARGINAL ZONE LYMPHOMA
por: Iatrou, Anastasia, et al.
Publicado: (2023)

ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia—update on methodological approaches and results interpretation
por: Malcikova, J., et al.
Publicado: (2018)

Impact of the Types and Relative Quantities of IGHV Gene Mutations in Predicting Prognosis of Patients With Chronic Lymphocytic Leukemia
por: Kaufman, Matthew, et al.
Publicado: (2022)

Editorial: The promise of immunogenetics for precision oncology
por: Vlachonikola, Elisavet, et al.
Publicado: (2023)

Differences in the immunoglobulin gene repertoires of IgG versus IgA multiple myeloma allude to distinct immunopathogenetic trajectories
por: Gkoliou, Glykeria, et al.
Publicado: (2023)

Validating genomic tools for precision medicine in CLL: ERIC leads the way
por: Wiestner, Adrian
Publicado: (2021)

Erratum to: Partial versus Productive Immunoglobulin Heavy Locus Rearrangements in Chronic Lymphocytic Leukemia: Implications for B-Cell Receptor Stereotypy
por: Tsakou, Eugenia, et al.
Publicado: (2013)

Tracing CLL-biased stereotyped immunoglobulin gene rearrangements in normal B cell subsets using a high-throughput immunogenetic approach
por: Colombo, Monica, et al.
Publicado: (2020)

CLL stereotyped B-cell receptor immunoglobulin sequences are recurrent in the B-cell repertoire of healthy individuals: Apparent lack of central and early peripheral tolerance censoring
por: Vergani, Stefano, et al.
Publicado: (2023)

Recent revelations and future directions using single-cell technologies in chronic lymphocytic leukemia
por: Oder, Blaž, et al.
Publicado: (2023)

Highly similar genomic landscapes in monoclonal B-cell lymphocytosis and ultra-stable chronic lymphocytic leukemia with low frequency of driver mutations
por: Agathangelidis, Andreas, et al.
Publicado: (2018)

T Cells in Chronic Lymphocytic Leukemia: A Two-Edged Sword
por: Vlachonikola, Elisavet, et al.
Publicado: (2021)

T Cell Defects and Immunotherapy in Chronic Lymphocytic Leukemia
por: Vlachonikola, Elisavet, et al.
Publicado: (2021)

Multidisciplinary diagnostics of chronic lymphocytic leukemia: European Research Initiative on CLL - ERIC recommendations
por: Zalcberg, Ilana, et al.
Publicado: (2020)

IMGT/HighV-QUEST Statistical Significance of IMGT Clonotype (AA) Diversity per Gene for Standardized Comparisons of Next Generation Sequencing Immunoprofiles of Immunoglobulins and T Cell Receptors
por: Aouinti, Safa, et al.
Publicado: (2015)

Correction: IMGT/HighV-QUEST Statistical Significance of IMGT Clonotype (AA) Diversity per Gene for Standardized Comparisons of Next Generation Sequencing Immunoprofiles of Immunoglobulins and T Cell Receptors
por: Aouinti, Safa, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_82goa0l7qcf2snlabn7oou61p1