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Targeted inhibition of osteoclastogenesis reveals the pathogenesis and therapeutics of bone loss under sympathetic neurostress

Sympathetic cues via the adrenergic signaling critically regulate bone homeostasis and contribute to neurostress-induced bone loss, but the mechanisms and therapeutics remain incompletely elucidated. Here, we reveal an osteoclastogenesis-centered functionally important osteopenic pathogenesis under...

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Detalles Bibliográficos
Autores principales: Sui, Bingdong, Liu, Jin, Zheng, Chenxi, Dang, Lei, Chen, Ji, Cao, Yuan, Zhang, Kaichao, Liu, Lu, Dang, Minyan, Zhang, Liqiang, Chen, Nan, He, Tao, Xuan, Kun, Jin, Fang, Zhang, Ge, Jin, Yan, Hu, Chenghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343357/
https://www.ncbi.nlm.nih.gov/pubmed/35915088
http://dx.doi.org/10.1038/s41368-022-00193-1