Xist exerts gene-specific silencing during XCI maintenance and impacts lineage-specific cell differentiation and proliferation during hematopoiesis

X chromosome inactivation (XCI) is a dosage compensation phenomenon that occurs in females. Initiation of XCI depends on Xist RNA, which triggers silencing of one of the two X chromosomes, except for XCI escape genes that continue to be biallelically expressed. In the soma XCI is stably maintained w...

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Detalles Bibliográficos
Autores principales: Yang, Tianqi, Ou, Jianhong, Yildirim, Eda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343370/
https://www.ncbi.nlm.nih.gov/pubmed/35915095
http://dx.doi.org/10.1038/s41467-022-32273-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343370/
https://www.ncbi.nlm.nih.gov/pubmed/35915095
http://dx.doi.org/10.1038/s41467-022-32273-5

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