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Lymphocyte Depletion Rate as a Biomarker of Radiation Dose to Circulating Lymphocytes During Fractionated Partial-Body Radiation Therapy

PURPOSE: Radiation causes exponential depletion of circulating lymphocyte populations; in turn, radiation-induced lymphopenia is associated with worse survival for many solid tumors, possibly owing to attenuated antitumor immune responses. Identifying reliable and reproducible methods of calculating...

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Detalles Bibliográficos
Autores principales: Ellsworth, Susannah G., Yalamanchali, Anirudh, Lautenschlaeger, Tim, Grossman, Stuart A., Grassberger, Clemens, Lin, Steven H., Mohan, Radhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343404/
https://www.ncbi.nlm.nih.gov/pubmed/35928987
http://dx.doi.org/10.1016/j.adro.2022.100959