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High-content imaging of human hepatic spheroids for researching the mechanism of duloxetine-induced hepatotoxicity

Duloxetine (DLX) has been approved for the successful treatment of psychiatric diseases, including major depressive disorder, diabetic neuropathy, fibromyalgia and generalized anxiety disorder. However, since the usage of DLX carries a manufacturer warning of hepatotoxicity given its implication in...

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Detalles Bibliográficos
Autores principales: Liu, Juan, Li, Ruihong, Zhang, Tingting, Xue, Rui, Li, Tingting, Li, Zheng, Zhuang, Xiaomei, Wang, Qi, Chen, Yu Ann, Dong, Jiahong, Zhang, Youzhi, Wang, Yunfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343405/
https://www.ncbi.nlm.nih.gov/pubmed/35915074
http://dx.doi.org/10.1038/s41419-022-05042-x