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Developmental modeling of hepatogenesis using obese iPSCs-hepatocyte differentiation uncovers pathological features

Obesity is a multigene disorder. However, in addition to genetic factors, environmental determinants also participate in developing obesity and related pathologies. Thus, obesity could be best described as a combination of genetic and environmental perturbations often having its origin during the ea...

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Detalles Bibliográficos
Autores principales: Varghese, Divya Saro, Alawathugoda, Thilina T., Sheikh, Muhammad Abid, Challagandla, Anil Kumar, Emerald, Bright Starling, Ansari, Suraiya A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343434/
https://www.ncbi.nlm.nih.gov/pubmed/35915082
http://dx.doi.org/10.1038/s41419-022-05125-9