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The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis
The cell cycle is tightly regulated by protein phosphorylation and ubiquitylation events. During mitosis, the multi-subunit cullin-RING E3 ubiquitin ligase APC/c functions as a molecular switch which signals for one cell to divide into two daughter cells, through the ubiquitylation and proteasomal d...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343455/ https://www.ncbi.nlm.nih.gov/pubmed/35915203 http://dx.doi.org/10.1038/s41598-022-16965-y |