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The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis

The cell cycle is tightly regulated by protein phosphorylation and ubiquitylation events. During mitosis, the multi-subunit cullin-RING E3 ubiquitin ligase APC/c functions as a molecular switch which signals for one cell to divide into two daughter cells, through the ubiquitylation and proteasomal d...

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Detalles Bibliográficos
Autores principales: Vaughan, Natalie, Scholz, Nico, Lindon, Catherine, Licchesi, Julien D. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343455/
https://www.ncbi.nlm.nih.gov/pubmed/35915203
http://dx.doi.org/10.1038/s41598-022-16965-y