Astrocyte-derived hepcidin controls iron traffic at the blood-brain-barrier via regulating ferroportin 1 of microvascular endothelial cells

Brain iron dysregulation associated with aging is closely related to motor and cognitive impairments in neurodegenerative diseases. The regulation of iron traffic at the blood-brain barrier (BBB) is crucial to maintain brain iron homeostasis. However, the specific mechanism has not been clarified in...

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Detalles Bibliográficos
Autores principales: You, Linhao, Yu, Pan-Pan, Dong, Tianyu, Guo, Wenhuan, Chang, Shiyang, Zheng, Bingjie, Ci, Yunzhe, Wang, Fudi, Yu, Peng, Gao, Guofen, Chang, Yan-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343463/
https://www.ncbi.nlm.nih.gov/pubmed/35915080
http://dx.doi.org/10.1038/s41419-022-05043-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343463/
https://www.ncbi.nlm.nih.gov/pubmed/35915080
http://dx.doi.org/10.1038/s41419-022-05043-w

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