Combi-seq for multiplexed transcriptome-based profiling of drug combinations using deterministic barcoding in single-cell droplets

Anti-cancer therapies often exhibit only short-term effects. Tumors typically develop drug resistance causing relapses that might be tackled with drug combinations. Identification of the right combination is challenging and would benefit from high-content, high-throughput combinatorial screens direc...

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Detalles Bibliográficos
Autores principales: Mathur, L., Szalai, B., Du, N. H., Utharala, R., Ballinger, M., Landry, J. J. M., Ryckelynck, M., Benes, V., Saez-Rodriguez, J., Merten, C. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343464/
https://www.ncbi.nlm.nih.gov/pubmed/35915108
http://dx.doi.org/10.1038/s41467-022-32197-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343464/
https://www.ncbi.nlm.nih.gov/pubmed/35915108
http://dx.doi.org/10.1038/s41467-022-32197-0

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