Activation of STING Based on Its Structural Features

The cGAS-cGAMP-STING pathway is an important innate immune signaling cascade responsible for the sensing of abnormal cytosolic double-stranded DNA (dsDNA), which is a hallmark of infection or cancers. Recently, tremendous progress has been made in the understanding of the STING activation mechanism...

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Detalles Bibliográficos
Autores principales: Hussain, Behzad, Xie, Yufeng, Jabeen, Uzma, Lu, Defen, Yang, Bo, Wu, Changxin, Shang, Guijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343627/
https://www.ncbi.nlm.nih.gov/pubmed/35928815
http://dx.doi.org/10.3389/fimmu.2022.808607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343627/
https://www.ncbi.nlm.nih.gov/pubmed/35928815
http://dx.doi.org/10.3389/fimmu.2022.808607

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