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Evaluation of rapid transepithelial electrical resistance (TEER) measurement as a metric of kidney toxicity in a high-throughput microfluidic culture system

Rapid non-invasive kidney-specific readouts are essential to maximizing the potential of microfluidic tissue culture platforms for drug-induced nephrotoxicity screening. Transepithelial electrical resistance (TEER) is a well-established technique, but it has yet to be evaluated as a metric of toxici...

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Detalles Bibliográficos
Autores principales: Shaughnessey, Erin M., Kann, Samuel H., Azizgolshani, Hesham, Black, Lauren D., Charest, Joseph L., Vedula, Else M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343646/
https://www.ncbi.nlm.nih.gov/pubmed/35915212
http://dx.doi.org/10.1038/s41598-022-16590-9