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Combined comparative genomics and clinical modeling reveals plasmid-encoded genes are independently associated with Klebsiella infection

Members of the Klebsiella pneumoniae species complex frequently colonize the gut and colonization is associated with subsequent infection. To identify genes associated with progression from colonization to infection, we undertook a case-control comparative genomics study. Concordant cases (N = 85),...

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Detalles Bibliográficos
Autores principales: Vornhagen, Jay, Roberts, Emily K., Unverdorben, Lavinia, Mason, Sophia, Patel, Alieysa, Crawford, Ryan, Holmes, Caitlyn L., Sun, Yuang, Teodorescu, Alexandra, Snitkin, Evan S., Zhao, Lili, Simner, Patricia J., Tamma, Pranita D., Rao, Krishna, Kaye, Keith S., Bachman, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343666/
https://www.ncbi.nlm.nih.gov/pubmed/35915063
http://dx.doi.org/10.1038/s41467-022-31990-1