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Combined comparative genomics and clinical modeling reveals plasmid-encoded genes are independently associated with Klebsiella infection
Members of the Klebsiella pneumoniae species complex frequently colonize the gut and colonization is associated with subsequent infection. To identify genes associated with progression from colonization to infection, we undertook a case-control comparative genomics study. Concordant cases (N = 85),...
Autores principales: | Vornhagen, Jay, Roberts, Emily K., Unverdorben, Lavinia, Mason, Sophia, Patel, Alieysa, Crawford, Ryan, Holmes, Caitlyn L., Sun, Yuang, Teodorescu, Alexandra, Snitkin, Evan S., Zhao, Lili, Simner, Patricia J., Tamma, Pranita D., Rao, Krishna, Kaye, Keith S., Bachman, Michael A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343666/ https://www.ncbi.nlm.nih.gov/pubmed/35915063 http://dx.doi.org/10.1038/s41467-022-31990-1 |
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