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Molecular and Cellular Response of the Myocardium (H9C2 Cells) Towards Hypoxia and HIF-1α Inhibition

INTRODUCTION: Oxidative phosphorylation is an essential feature of Animalian life. Multiple adaptations have developed to protect against hypoxia, including hypoxia-inducible-factors (HIFs). The major role of HIFs may be in protecting against oxidative stress, not the preservation of high-energy pho...

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Detalles Bibliográficos
Autores principales: Osuru, Hari Prasad, Lavallee, Matthew, Thiele, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343679/
https://www.ncbi.nlm.nih.gov/pubmed/35928940
http://dx.doi.org/10.3389/fcvm.2022.711421