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Increased TGFβ1 and SMAD3 Contribute to Age-Related Aortic Valve Calcification

AIMS: Calcific aortic valve disease (CAVD) is a progressive heart disease that is particularly prevalent in elderly patients. The current treatment of CAVD is surgical valve replacement, but this is not a permanent solution, and it is very challenging for elderly patients. Thus, a pharmacological in...

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Detalles Bibliográficos
Autores principales: Chakrabarti, Mrinmay, Bhattacharya, Aniket, Gebere, Mengistu G., Johnson, John, Ayub, Zeeshan A., Chatzistamou, Ioulia, Vyavahare, Narendra R., Azhar, Mohamad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343688/
https://www.ncbi.nlm.nih.gov/pubmed/35928937
http://dx.doi.org/10.3389/fcvm.2022.770065