Tumor Suppressor DAPK1 Catalyzes Adhesion Assembly on Rigid but Anoikis on Soft Matrices

Cancer cells normally grow on soft surfaces due to impaired mechanosensing of the extracellular matrix rigidity. Upon restoration of proper mechanosensing, cancer cells undergo apoptosis on soft surfaces (anoikis) like most normal cells. However, the link between mechanosensing and activation of ano...

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Detalles Bibliográficos
Autores principales: Qin, Ruifang, Melamed, Shay, Yang, Bo, Saxena, Mayur, Sheetz, Michael P., Wolfenson, Haguy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343699/
https://www.ncbi.nlm.nih.gov/pubmed/35927990
http://dx.doi.org/10.3389/fcell.2022.959521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343699/
https://www.ncbi.nlm.nih.gov/pubmed/35927990
http://dx.doi.org/10.3389/fcell.2022.959521

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