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Rechallenge of denosumab in advanced giant cell tumor of the bone after atypical femur fracture: A case report and review of literature

Giant cell tumor of the bone (GCTB) is a locally aggressive neoplasm where surgery is often curative. However, it can rarely give rise to distant metastases. Currently, the only available active therapeutic option for unresectable GCTB is denosumab, an anti-RANKL monoclonal antibody that dampens the...

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Detalles Bibliográficos
Autores principales: Nasca, Vincenzo, Frezza, Anna Maria, Morosi, Carlo, Buonomenna, Ciriaco, Parafioriti, Antonina, Zappalà, Giorgio, Bini, Federica, Casali, Paolo Giovanni, Loppini, Mattia, Stacchiotti, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343706/
https://www.ncbi.nlm.nih.gov/pubmed/35928864
http://dx.doi.org/10.3389/fonc.2022.953149