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Synthesis and evaluation of diterpenic Mannich bases as antiviral agents against influenza A and SARS-CoV-2

A chemical library was constructed based on the resin acids (abietic, dehydroabietic, and 12-formylabietic) and its diene adducts (maleopimaric and quinopimaric acid derivatives). The one-pot three-component CuCl-catalyzed aminomethylation of the abietane diterpenoid propargyl derivatives was carrie...

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Detalles Bibliográficos
Autores principales: Tret’yakova, Elena V., Ma, Xinyuan, Kazakova, Oxana B., Shtro, Anna A., Petukhova, Galina D., Klabukov, Artem M., Dyatlov, Danil S., Smirnova, Anna A., Xu, Huan, Xiao, Sulong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Phytochemical Society of Europe. Published by Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343747/
https://www.ncbi.nlm.nih.gov/pubmed/35935343
http://dx.doi.org/10.1016/j.phytol.2022.07.010