Single-Cell Transcriptomics Reveals Killing Mechanisms of Antitumor Cytotoxic CD4(+) TCR-T Cells

T cell receptor-engineered T cells (TCR-Ts) have emerged as potent cancer immunotherapies. While most research focused on classical cytotoxic CD8(+) T cells, the application of CD4(+) T cells in adoptive T cell therapy has gained much interest recently. However, the cytotoxic mechanisms of CD4(+) TC...

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Detalles Bibliográficos
Autores principales: Liang, Yanling, Xu, Qumiao, Liu, Songming, Li, Jie, Wang, Fei, Li, Ziyi, Liao, Lijuan, Lu, Yuting, Li, Yijian, Mu, Feng, Sun, Hai-Xi, Zhu, Linnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343810/
https://www.ncbi.nlm.nih.gov/pubmed/35928827
http://dx.doi.org/10.3389/fimmu.2022.939940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343810/
https://www.ncbi.nlm.nih.gov/pubmed/35928827
http://dx.doi.org/10.3389/fimmu.2022.939940

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