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A Quantitative Systems Pharmacology Model of Liver Lipid Metabolism for Investigation of Non-Alcoholic Fatty Liver Disease

Non-alcoholic fatty liver disease is a metabolic and inflammatory disease that afflicts many people worldwide and presently has few treatment options. To enhance the preclinical to clinical translation and the design of early clinical trials for novel therapeutics, we developed a Quantitative System...

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Detalles Bibliográficos
Autores principales: Rieger, Theodore R., Allen, Richard J., Musante, Cynthia J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343875/
https://www.ncbi.nlm.nih.gov/pubmed/35928268
http://dx.doi.org/10.3389/fphar.2022.910789