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Proinflammatory mediators, TNFα, IFNγ, and thrombin, directly induce lymphatic capillary tube regression

In this work, we sought to investigate the direct effects of proinflammatory mediators on lymphatic endothelial cell (LEC) capillaries and whether they might induce regression. Our laboratory has developed novel in-vitro, serum-free, lymphatic tubulogenesis assay models whereby human LEC tube networ...

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Detalles Bibliográficos
Autores principales: Kemp, Scott S., Penn, Marlena R., Koller, Gretchen M., Griffin, Courtney T., Davis, George E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343954/
https://www.ncbi.nlm.nih.gov/pubmed/35927983
http://dx.doi.org/10.3389/fcell.2022.937982