Nuclear Localization Signals for Optimization of Genetically Encoded Tools in Neurons

Nuclear transport in neurons differs from that in non-neuronal cells. Here we developed a non-opsin optogenetic tool (OT) for the nuclear export of a protein of interest induced by near-infrared (NIR) light. In darkness, nuclear import reverses the OT action. We used this tool for comparative analys...

Descripción completa

Detalles Bibliográficos
Autores principales: Karasev, Maksim M., Baloban, Mikhail, Verkhusha, Vladislav V., Shcherbakova, Daria M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344056/
https://www.ncbi.nlm.nih.gov/pubmed/35927988
http://dx.doi.org/10.3389/fcell.2022.931237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344056/
https://www.ncbi.nlm.nih.gov/pubmed/35927988
http://dx.doi.org/10.3389/fcell.2022.931237

Ejemplares similares