Cargando…
Nuclear Localization Signals for Optimization of Genetically Encoded Tools in Neurons
Nuclear transport in neurons differs from that in non-neuronal cells. Here we developed a non-opsin optogenetic tool (OT) for the nuclear export of a protein of interest induced by near-infrared (NIR) light. In darkness, nuclear import reverses the OT action. We used this tool for comparative analys...
Autores principales: | Karasev, Maksim M., Baloban, Mikhail, Verkhusha, Vladislav V., Shcherbakova, Daria M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344056/ https://www.ncbi.nlm.nih.gov/pubmed/35927988 http://dx.doi.org/10.3389/fcell.2022.931237 |
Ejemplares similares
-
Single-component near-infrared optogenetic systems for gene transcription regulation
por: Kaberniuk, Andrii A., et al.
Publicado: (2021) -
Design and Initial Characterization of a Small Near-Infrared Fluorescent Calcium Indicator
por: Matlashov, Mikhail E., et al.
Publicado: (2022) -
Bright blue-shifted fluorescent proteins with Cys in the GAF domain engineered from bacterial phytochromes: fluorescence mechanisms and excited-state dynamics
por: Hontani, Yusaku, et al.
Publicado: (2016) -
Bright monomeric near-infrared fluorescent proteins as tags and biosensors for multiscale imaging
por: Shcherbakova, Daria M., et al.
Publicado: (2016) -
Designing brighter near-infrared fluorescent proteins: insights from structural and biochemical studies
por: Baloban, Mikhail, et al.
Publicado: (2017)