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Therapeutic potential of human stem cell transplantations for Vanishing White Matter: A quest for the Goldilocks graft

INTRODUCTION: Vanishing white matter (VWM) is a leukodystrophy that leads to neurological dysfunction and early death. Astrocytes are indicated as therapeutic target, because of their central role in VWM pathology. Previous cell replacement therapy using primary mouse glial precursors phenotypically...

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Detalles Bibliográficos
Autores principales: Hillen, Anne E. J., Leferink, Prisca S., Breeuwsma, Nicole B., Dooves, Stephanie, Bergaglio, Talia, Van der Knaap, Marjo S., Heine, Vivi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344080/
https://www.ncbi.nlm.nih.gov/pubmed/35778846
http://dx.doi.org/10.1111/cns.13872