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Unraveling the role of Epac1‐SOCS3 signaling in the development of neonatal‐CRD‐induced visceral hypersensitivity in rats

AIMS: Visceral hypersensitivity in irritable bowel syndrome (IBS) is widespread, but effective therapies for it remain elusive. As a canonical anti‐inflammatory protein, suppressor of cytokine signaling 3 (SOCS3) reportedly relays exchange protein 1 directly activated by cAMP (Epac1) signaling and i...

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Detalles Bibliográficos
Autores principales: Huang, Si‐Ting, Chen, Bin‐Bin, Song, Zhi‐Jing, Tang, Hui‐Li, Hua, Rong, Zhang, Yong‐Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344090/
https://www.ncbi.nlm.nih.gov/pubmed/35702948
http://dx.doi.org/10.1111/cns.13880