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Comparison of ticagrelor and clopidogrel in the treatment of patients with coronary heart disease carrying CYP2C19 loss of function allele

BACKGROUND: Clopidogrel is a traditional P2Y12 receptor inhibitor that is widely used in clinical practice, but there are significant individual differences in its therapeutic effect. Carriers of the CYP2C19 deletion allele have a higher risk of adverse cardiovascular events than non-carriers. METHO...

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Detalles Bibliográficos
Autores principales: Qian, Wenwen, Chen, Liang, Zhang, Lizhu, Gao, Mingzhu, Wang, Chunxia, Qian, Xi, Yang, Chengjian, Lin, Yahui, Han, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344405/
https://www.ncbi.nlm.nih.gov/pubmed/35928614
http://dx.doi.org/10.21037/jtd-22-740