The Dual Roles of MAGE-C2 in p53 Ubiquitination and Cell Proliferation Through E3 Ligases MDM2 and TRIM28

The tumor suppressor p53 is critical for the maintenance of genome stability and protection against tumor malignant transformation, and its homeostasis is usually regulated by ubiquitination. MDM2 is a major E3 ligase of p53 ubiquitination, and its activity is enhanced by TRIM28. TRIM28 also indepen...

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Detalles Bibliográficos
Autores principales: Liu, Yunshan, Cao, Beibei, Hu, Liqiao, Ye, Jingjing, Tian, Wei, He, Xiaojing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344466/
https://www.ncbi.nlm.nih.gov/pubmed/35927984
http://dx.doi.org/10.3389/fcell.2022.922675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344466/
https://www.ncbi.nlm.nih.gov/pubmed/35927984
http://dx.doi.org/10.3389/fcell.2022.922675

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