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Identifying genetic markers enriched by brain imaging endophenotypes in Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) is a complex neurodegenerative disorder and the most common type of dementia. AD is characterized by a decline of cognitive function and brain atrophy, and is highly heritable with estimated heritability ranging from 60 to 80[Formula: see text] . The most straigh...

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Detalles Bibliográficos
Autores principales: Kim, Mansu, Wu, Ruiming, Yao, Xiaohui, Saykin, Andrew J., Moore, Jason H., Shen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344647/
https://www.ncbi.nlm.nih.gov/pubmed/35915443
http://dx.doi.org/10.1186/s12920-022-01323-8