Cargando…
Identifying genetic markers enriched by brain imaging endophenotypes in Alzheimer’s disease
BACKGROUND: Alzheimer’s disease (AD) is a complex neurodegenerative disorder and the most common type of dementia. AD is characterized by a decline of cognitive function and brain atrophy, and is highly heritable with estimated heritability ranging from 60 to 80[Formula: see text] . The most straigh...
Autores principales: | Kim, Mansu, Wu, Ruiming, Yao, Xiaohui, Saykin, Andrew J., Moore, Jason H., Shen, Li |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344647/ https://www.ncbi.nlm.nih.gov/pubmed/35915443 http://dx.doi.org/10.1186/s12920-022-01323-8 |
Ejemplares similares
-
Mining High-Level Imaging Genetic Associations via Clustering AD Candidate Variants with Similar Brain Association Patterns
por: Wu, Ruiming, et al.
Publicado: (2022) -
Identifying imaging genetic associations via regional morphometricity estimation
por: Bao, Jingxuan, et al.
Publicado: (2022) -
Two-dimensional enrichment analysis for mining high-level imaging genetic associations
por: Yao, Xiaohui, et al.
Publicado: (2016) -
Identifying highly heritable brain amyloid phenotypes through mining Alzheimer’s imaging and sequencing biobank data
por: Bao, Jingxuan, et al.
Publicado: (2022) -
Genome-Wide Association Analysis across Endophenotypes in Alzheimer’s Disease: Main Effects and Disease Stage-Specific Interactions
por: Rosewood, Thea J., et al.
Publicado: (2023)