Therapeutic potential of inhibiting histone 3 lysine 27 demethylases: a review of the literature

Histone 3 lysine 27 (H3K27) demethylation constitutes an important epigenetic mechanism of gene activation. It is mediated by the Jumonji C domain-containing lysine demethylases KDM6A and KDM6B, both of which have been implicated in a wide myriad of diseases, including blood and solid tumours, autoi...

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Detalles Bibliográficos
Autores principales: Abu-Hanna, Jeries, Patel, Jigisha A., Anastasakis, Evangelos, Cohen, Richard, Clapp, Lucie H., Loizidou, Marilena, Eddama, Mohammad M. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344682/
https://www.ncbi.nlm.nih.gov/pubmed/35915507
http://dx.doi.org/10.1186/s13148-022-01305-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344682/
https://www.ncbi.nlm.nih.gov/pubmed/35915507
http://dx.doi.org/10.1186/s13148-022-01305-8

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