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Targeted delivery of irinotecan to colon cancer cells using epidermal growth factor receptor-conjugated liposomes

BACKGROUND: CPT-11 (irinotecan) is one of the most efficient agents used for colorectal cancer chemotherapy. However, as for many other chemotherapeutic drugs, how to minimize the side effects of CPT-11 still needs to be thoroughly described. OBJECTIVES: This study aimed to develop the CPT-11-loaded...

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Detalles Bibliográficos
Autores principales: Liu, Yongwei, Li, Xinghui, Pen, Renqun, Zuo, Wei, Chen, Ya, Sun, Xiuying, Gou, Juhua, Guo, Qianwen, Wen, Maoling, Li, Wuqi, Yu, Shuangjiang, Liu, Hao, Huang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344698/
https://www.ncbi.nlm.nih.gov/pubmed/35918704
http://dx.doi.org/10.1186/s12938-022-01012-8