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A fetal fraction enrichment method reduces false negatives and increases test success rate of fetal chromosome aneuploidy detection in early pregnancy loss

OBJECTIVE: We and others have previously demonstrated that the size-selection enrichment method could remarkably improve fetal fraction (FF) in the early gestational age (GA, 12–13 weeks), suggesting that 9 or 10 weeks should not be used as a threshold for GA in size-selection noninvasive prenatal s...

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Detalles Bibliográficos
Autores principales: Qiao, Longwei, Zhang, Bin, Wu, Xiaojuan, Zhang, Chunhua, Xue, Ying, Tang, Hui, Tang, Haoyu, Shi, Jingye, Liang, Yuting, Yu, Bin, Wang, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344718/
https://www.ncbi.nlm.nih.gov/pubmed/35918754
http://dx.doi.org/10.1186/s12967-022-03555-9