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Regulation of cholesterol homeostasis in health and diseases: from mechanisms to targeted therapeutics
Disturbed cholesterol homeostasis plays critical roles in the development of multiple diseases, such as cardiovascular diseases (CVD), neurodegenerative diseases and cancers, particularly the CVD in which the accumulation of lipids (mainly the cholesteryl esters) within macrophage/foam cells underne...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344793/ https://www.ncbi.nlm.nih.gov/pubmed/35918332 http://dx.doi.org/10.1038/s41392-022-01125-5 |