Activation of adenosine A3 receptor attenuates progression of osteoarthritis through inhibiting the NLRP3/caspase‐1/GSDMD induced signalling

The specific adenosine A3 receptor (A3AR) agonist (CF101) has potential for inflammation and pain in various disease, such as arthritis, cancer and neuropathic pain, while the role of A3AR in post‐traumatic OA and the underlying mechanism is largely unknown. CF101 was orally administrated in OA rats...

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Detalles Bibliográficos
Autores principales: Bai, Hui, Zhang, Zhiheng, Liu, Lin, Wang, Xinyu, Song, Xiaopeng, Gao, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344816/
https://www.ncbi.nlm.nih.gov/pubmed/35775127
http://dx.doi.org/10.1111/jcmm.17438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344816/
https://www.ncbi.nlm.nih.gov/pubmed/35775127
http://dx.doi.org/10.1111/jcmm.17438

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