Lamivudine, a reverse transcriptase inhibitor, rescues cognitive deficits in a mouse model of down syndrome

An elevated activity of retrotransposons is increasingly recognized to be implicated in a wide range of neurodegenerative and neurodevelopmental diseases. Down syndrome (DS) is the most common genetic disorder associated with intellectual disability and a genetic form of Alzheimer's disease. Fo...

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Detalles Bibliográficos
Autores principales: Martinez de Lagran, Maria, Elizalde‐Torrent, Aleix, Paredes, Roger, Clotet, Bonaventura, Dierssen, Mara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344819/
https://www.ncbi.nlm.nih.gov/pubmed/35762509
http://dx.doi.org/10.1111/jcmm.17411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344819/
https://www.ncbi.nlm.nih.gov/pubmed/35762509
http://dx.doi.org/10.1111/jcmm.17411

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