Ligand-based design, synthesis, computational insights, and in vitro studies of novel N-(5-Nitrothiazol-2-yl)-carboxamido derivatives as potent inhibitors of SARS-CoV-2 main protease

The global outbreak of the COVID-19 pandemic provokes scientists to make a prompt development of new effective therapeutic interventions for the battle against SARS-CoV-2. A new series of N-(5-nitrothiazol-2-yl)-carboxamido derivatives were designed and synthesised based on the structural optimisati...

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Detalles Bibliográficos
Autores principales: Elagawany, Mohamed, Elmaaty, Ayman Abo, Mostafa, Ahmed, Abo Shama, Noura M., Santali, Eman Y., Elgendy, Bahaa, Al-Karmalawy, Ahmed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344964/
https://www.ncbi.nlm.nih.gov/pubmed/35912578
http://dx.doi.org/10.1080/14756366.2022.2105322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344964/
https://www.ncbi.nlm.nih.gov/pubmed/35912578
http://dx.doi.org/10.1080/14756366.2022.2105322

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