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Grouping of UVCB Substances with Dose-Response Transcriptomics Data from Human Cell-Based Assays

The application of in vitro biological assays as new approach methodologies (NAMs) to support grouping of UVCB (unknown or variable composition, complex reaction products, and biological materials) substances has recently been demonstrated. In addition to cell-based phenotyping as NAMs, in vitro tra...

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Detalles Bibliográficos
Autores principales: House, John S., Grimm, Fabian A., Klaren, William D., Dalzell, Abigail, Kuchi, Srikeerthana, Zhang, Shu-Dong, Lenz, Klaus, Boogaard, Peter J., Ketelslegers, Hans B., Gant, Timothy W., Rusyn, Ivan, Wright, Fred A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9344966/
https://www.ncbi.nlm.nih.gov/pubmed/35288757
http://dx.doi.org/10.14573/altex.2107051