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Effects of subanaesthetic S-ketamine on postoperative delirium and cognitive function in elderly patients undergoing non-cardiac thoracic surgery: a protocol for a randomised, double-blinded, placebo-controlled and positive-controlled, non-inferiority trial (SKED trial)

INTRODUCTION: Postoperative delirium (POD) is a common and distressing complication after thoracic surgery. S-ketamine has neuroprotective properties as a dissociative anaesthetic. Emerging literature has indicated that S-ketamine can reduce cognitive impairment in patients with depression. However,...

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Detalles Bibliográficos
Autores principales: Wei, Wei, Zhang, Anyu, Liu, Lv, Zheng, Xi, Tang, Chunlin, Zhou, Ming, Gu, Yu, Yao, Yonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345033/
https://www.ncbi.nlm.nih.gov/pubmed/35914911
http://dx.doi.org/10.1136/bmjopen-2022-061535