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Synaptic NMDA receptor activity at resting membrane potentials

NMDA receptors (NMDARs) are crucial for glutamatergic synaptic signaling in the mammalian central nervous system. When activated by glutamate and glycine/D-serine, the NMDAR ion channel can open, but current flux is further regulated by voltage-dependent block conferred by extracellular Mg(2+) ions....

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Detalles Bibliográficos
Autores principales: Chiu, Delia N., Carter, Brett C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345169/
https://www.ncbi.nlm.nih.gov/pubmed/35928574
http://dx.doi.org/10.3389/fncel.2022.916626