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Mouse Model of Weak Depression Exhibiting Suppressed cAMP Signaling in the Amygdala, Lower Lipid Catabolism in Liver, and Correlated Gut Microbiota

To establish a mouse model of weak depression, we raised 6-week-old C57BL/6N mice in single (SH) or group housing (GH) conditions for 2 weeks. The SH group showed less social interaction with stranger mice, learning disability in behavioral tests, and lower plasma corticosterone levels. The cecal mi...

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Detalles Bibliográficos
Autores principales: Shimada, Kousuke, Nohara, Masakatsu, Yasuoka, Akihito, Kamei, Asuka, Shinozaki, Fumika, Kondo, Kaori, Inoue, Ryo, Kondo, Takashi, Abe, Keiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345170/
https://www.ncbi.nlm.nih.gov/pubmed/35928791
http://dx.doi.org/10.3389/fnbeh.2022.841450