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Osteocytic cells exposed to titanium particles increase sclerostin expression and inhibit osteoblastic cell differentiation mostly via direct cell‐to‐cell contact

The mechanism underlying induction of periprosthetic osteolysis by wear particles remains unclear. In this study, cultured MLO‐Y4 osteocytic cells were exposed to different concentrations of titanium (Ti) particles. The results showed that Ti particles increased expression of the osteocytic marker S...

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Detalles Bibliográficos
Autores principales: Chai, Hao, Zhang, Zai Hang, Fang, Jing Yi, She, Chang, Geng, De Chun, Xu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345295/
https://www.ncbi.nlm.nih.gov/pubmed/35762300
http://dx.doi.org/10.1111/jcmm.17460