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Osteocytic cells exposed to titanium particles increase sclerostin expression and inhibit osteoblastic cell differentiation mostly via direct cell‐to‐cell contact
The mechanism underlying induction of periprosthetic osteolysis by wear particles remains unclear. In this study, cultured MLO‐Y4 osteocytic cells were exposed to different concentrations of titanium (Ti) particles. The results showed that Ti particles increased expression of the osteocytic marker S...
Autores principales: | Chai, Hao, Zhang, Zai Hang, Fang, Jing Yi, She, Chang, Geng, De Chun, Xu, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345295/ https://www.ncbi.nlm.nih.gov/pubmed/35762300 http://dx.doi.org/10.1111/jcmm.17460 |
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