Structural analysis of spike proteins from SARS-CoV-2 variants of concern highlighting their functional alterations

Aim: Mutations in the SARS-CoV-2 spike (S) protein have dramatically changed the transmissibility and pathogenicity of the virus. Therefore, we studied the binding affinity of Omicron spike-receptor binding domain (S-RBD) with human ACE2 receptor. Materials & methods: We used pyDockWEB and HADDO...

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Detalles Bibliográficos
Autores principales: Solanki, Kundan, Rajpoot, Sajjan, Kumar, Ashutosh, J Zhang, Kam Y, Ohishi, Tomokazu, Hirani, Nik, Wadhonkar, Khandu, Patidar, Pramod, Pan, Qiuwei, Baig, Mirza S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345306/
https://www.ncbi.nlm.nih.gov/pubmed/35935449
http://dx.doi.org/10.2217/fvl-2022-0003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345306/
https://www.ncbi.nlm.nih.gov/pubmed/35935449
http://dx.doi.org/10.2217/fvl-2022-0003

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