Cargando…
Structural analysis of spike proteins from SARS-CoV-2 variants of concern highlighting their functional alterations
Aim: Mutations in the SARS-CoV-2 spike (S) protein have dramatically changed the transmissibility and pathogenicity of the virus. Therefore, we studied the binding affinity of Omicron spike-receptor binding domain (S-RBD) with human ACE2 receptor. Materials & methods: We used pyDockWEB and HADDO...
Autores principales: | Solanki, Kundan, Rajpoot, Sajjan, Kumar, Ashutosh, J Zhang, Kam Y, Ohishi, Tomokazu, Hirani, Nik, Wadhonkar, Khandu, Patidar, Pramod, Pan, Qiuwei, Baig, Mirza S |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Future Medicine Ltd
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345306/ https://www.ncbi.nlm.nih.gov/pubmed/35935449 http://dx.doi.org/10.2217/fvl-2022-0003 |
Ejemplares similares
-
In-Silico Design of a Novel Tridecapeptide Targeting Spike Protein of SARS-CoV-2 Variants of Concern
por: Rajpoot, Sajjan, et al.
Publicado: (2021) -
A Novel Therapeutic Peptide Blocks SARS-CoV-2 Spike Protein Binding with Host Cell ACE2 Receptor
por: Rajpoot, Sajjan, et al.
Publicado: (2021) -
Epigallocatechin gallate (EGCG) attenuates severe acute respiratory coronavirus disease 2 (SARS-CoV-2) infection by blocking the interaction of SARS-CoV-2 spike protein receptor-binding domain to human angiotensin-converting enzyme 2
por: Ohishi, Tomokazu, et al.
Publicado: (2022) -
Repurposing dyphylline as a pan-coronavirus antiviral therapy
por: Wang, Yining, et al.
Publicado: (2022) -
Structure-Based Design of Novel Peptidomimetics Targeting the SARS-CoV-2 Spike Protein
por: Alagumuthu, Manikandan, et al.
Publicado: (2020)