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DYRK1a Inhibitor Mediated Rescue of Drosophila Models of Alzheimer’s Disease-Down Syndrome Phenotypes

Alzheimer’s disease (AD) is the most common neurodegenerative disease which is becoming increasingly prevalent due to ageing populations resulting in huge social, economic, and health costs to the community. Despite the pathological processing of genes such as Amyloid Precursor Protein (APP) into Am...

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Detalles Bibliográficos
Autores principales: Zhu, Bangfu, Parsons, Tom, Stensen, Wenche, Mjøen Svendsen, John S., Fugelli, Anders, Hodge, James J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345315/
https://www.ncbi.nlm.nih.gov/pubmed/35928283
http://dx.doi.org/10.3389/fphar.2022.881385