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Glucose deprivation reduces proliferation and motility, and enhances the anti-proliferative effects of paclitaxel and doxorubicin in breast cell lines in vitro

BACKGROUND: Breast cancer chemotherapy with high dose alkylating agents is severely limited by their collateral toxicity to crucial normal tissues such as immune and gut cells. Taking advantage of the selective dependence of cancer cells on high glucose and combining glucose deprivation with these a...

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Detalles Bibliográficos
Autores principales: Khajah, Maitham A., Khushaish, Sarah, Luqmani, Yunus A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345370/
https://www.ncbi.nlm.nih.gov/pubmed/35917304
http://dx.doi.org/10.1371/journal.pone.0272449