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Oxidant stress evoked damage in rat hepatocyte leading to triggered nitric oxide synthase (NOS) levels on long term consumption of aspartame

This study investigates how long-term (40 mg/kg b.wt) consumption of aspartame can alter the antioxidant status, stress pathway genes, and apoptotic changes in the liver of Wistar albino rats. Numerous controversial reports are available on the use of aspartame as it releases methanol as one of its...

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Detalles Bibliográficos
Autores principales: Ashok, Iyaswamy, Sheeladevi, Rathinasamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taiwan Food and Drug Administration 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9345445/
https://www.ncbi.nlm.nih.gov/pubmed/28911484
http://dx.doi.org/10.1016/j.jfda.2014.07.011